hrp0097p1-408 | Adrenals and HPA Axis | ESPE2023

Primary Adrenal Insufficiency in Children: Genetic and Clinical Characterization of a Large Cohort in Thailand

Chaisiwamongkol Ratikorn , Kwanyuen Thamakorn , Tantirukdham Nithiphut , Yeetong Patra , Shotelersuk Vorasuk , Sahakitrungruang Taninee

Background: Primary adrenal insufficiency (PAI) is a rare but life-threatening condition. Its diagnosis is frequently delayed due to its nonspecific and diverse symptoms. The etiology of PAI is heterogeneous and varies among populations.Objective: The objective of this study was to characterize the clinical and hormonal phenotypes of Thai children with PAI and to determine the underlying genetic defects.<p class="abs...